Whenever you suffer pain, keep in mind that it's nothing to be ashamed of and that it can't degrade your guiding intelligence, nor keep it from acting rationally and for the common good. And in most cases you should be helped by the saying of Epicurus, that pain is never unbearable or unending, so you can remember these limits and not add to them in your imagination. Remember too that many common annoyances are pain in disguise, such as sleepiness, fever and loss of appetite. When they start to get you down, tell yourself you are giving in to pain.
A person who doesn't know what the universe is doesn't know who they are. A person who doesn't know their purpose in life doesn't know who they are or what the universe is. A person who doesn't know any of these things doesn't know why they are here. So what to make of people who seek or avoid the praise of those who have no knowledge of where or who they are?
What if someone despises me? Let me see to it. But I will see to it that I won't be found doing or saying anything contemptible. What if someone hates me? Let me see to that. But I will see to it that I'm kind and good-natured to all, and prepared to show even the hater where they went wrong. Not in a critical way, or to show off my patience, but genuinely and usefully.
[Before making a decision] The first thing to do – don't get worked up. For everything happens according to the nature of all things, and in a short time you'll be nobody and nowhere even as the great emperors Hadrian and Augustus are now. The next thing to do – consider carefully the task at hand for what it is, while remembering that your purpose is to be a good human being. Get straight to doing what nature requires of you, and speak as you see most just and fitting – with kindness, modesty, and sincerity.
In your actions, don't procrastinate. In your conversations, don't confuse. In your thoughts, don't wander. In your soul, don't be passive or aggressive. In your life, don't be all about business.
Whatever happens to you has been waiting to happen since the beginning of time. The twining strands of fate wove both of them together: your own existence and the things that happen to you.